Brissett Takes the Cardinals to SoFi Without Marvin Harrison Jr. to Face Stafford’s Rams
Arizona traded Marvin Harrison Jr. to Houston during its 45-21 loss to Detroit and heads to SoFi Stadium at 1-4, losers of four straight. The Rams are 2-2 and host Buffalo on Monday night before this one. Los Angeles beat the Cardinals twice last season, 45-17 and 37-20. The posted line is LAR -12.5 with a total of
52.5, and the contract below prices the win outright.
Kickoff
1:05 PM PT
4:05 PM ET, Sun, Oct 18
Stadium
SoFi Stadium
Inglewood
On TV
FOX
national window
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Arizona Cardinals are 1-4. Los Angeles Rams are 2-2. The posted line has Los Angeles Rams favoured by 12.5, with a total of 52.5. Kickoff is 4:05 PM ET on Sunday, October 18 at SoFi Stadium, Inglewood.
The storyline. Arizona traded Marvin Harrison Jr. to Houston during its 45-21 loss to Detroit and heads to SoFi Stadium at 1-4, losers of four straight. The Rams are 2-2 and host Buffalo on Monday night before this one. Los Angeles beat the Cardinals twice last season, 45-17 and 37-20.
Eight storylines for Cardinals at Rams
Marvin Harrison Jr. is gone
The Cardinals traded Marvin Harrison Jr. to the Houston Texans during the first quarter of their 45-21 loss to Detroit on October 11, and he was inactive and not at the stadium. Arizona had told him he would not play against the Lions while the deal was finished. The No. 4 pick of the 2024 draft had 5 catches for 85 yards and a touchdown in the first four games. AP recap via CBS Sports · ESPN on the Harrison trade
Four straight losses after a road win
Arizona opened with a 26-14 win at the Chargers, then lost 31-7 to Seattle, 36-30 at San Francisco, 36-24 at the Giants and 45-21 to Detroit. The Cardinals have allowed 37 points a game during the losing streak and 32.4 a game for the season, and they have lost nine straight home games. ESPN game page · AP recap via CBS Sports
A first-year coach takes the blame
Detroit scored on seven straight drives and went 4 for 4 on fourth down. First-year coach Mike LaFleur said afterward: “Anytime there’s a blowout like this, it starts with coaching.” The AP wrote that the losing streak has raised questions about defensive coordinator Nick Rallis’ job; LaFleur did not say whether changes were coming. AP recap via CBS Sports
Jacoby Brissett keeps throwing
Brissett has 1,110 passing yards, 9 touchdowns and 5 interceptions. He threw for 292 yards and three touchdowns against Detroit, two of them to Teagan Quitoriano. A week earlier at the Giants, three interceptions included a walk-off pick-six. He is 2-15 as a starter since replacing Kyler Murray last season. ESPN game page · AP recap via CBS Sports · NBC Sports
The Rams play Buffalo first
Los Angeles is 2-2 and hosts Buffalo on Monday night before this game: a 27-7 loss to San Francisco, a 28-6 win over the Giants, a 30-26 loss at Denver and a 24-20 win at Philadelphia. The Rams allow 255.8 yards a game, per ESPN. Matthew Stafford has six interceptions after throwing eight all of last season, and the Rams have committed multiple turnovers in four straight games. ESPN game page · ESPN Bills-Rams preview
Aaron Donald is back, Myles Garrett is not yet
Aaron Donald came out of retirement at the end of August, missed Week 4 with back soreness and practiced in full Friday with plans to play against Buffalo. Myles Garrett, the reigning Defensive Player of the Year, whom the Rams got from Cleveland for Jared Verse and three draft picks, is on injured reserve after knee surgery. Sean McVay said he is making “good progress” but that the Rams are unlikely to open his 21-day practice window next week. ESPN on Aaron Donald · ESPN on Myles Garrett
The Rams swept Arizona last season
Los Angeles beat the Cardinals 45-17 in Arizona on December 7, 2025, and 37-20 in Los Angeles on January 4, 2026. Arizona finished 3-14 under Jonathan Gannon. Pro-Football-Reference
The line
DraftKings had the Rams by 12.5 with a total of 52.5, the Rams at -675 and the Cardinals at +490, as read on ESPN on October 12. Lines move through the week; the live Kalshi price is on this page. ESPN odds (DraftKings)
Cardinals vs Rams injury report
Statuses are from ESPN’s NFL injury page, read Friday, October 16, at 10:45 AM PT, with the practice notes it carries. Teams set final game statuses on Friday afternoon and inactives come out 90 minutes before kickoff, so a Questionable here can still move.
Player
Team, pos
Status
What it changes
Jeremiyah Love
ARI, RB
Questionable
Ankle. Still sidelined at practice Thursday, per ESPN’s Adam Schefter.
James Conner
ARI, RB
Injured reserve
Foot. Close to practicing, but his window is not expected to open this week.
Weeks 1-5: 5-56, 2-18, 11-89, 7-95, 4-30 on 51 targets.
29 catches for 288 yards, with 17 targets at San Francisco. He is Arizona’s most-targeted wide receiver, and Harrison’s 13 targets leave with the trade. He also threw a 7-yard completion against Detroit.
Weeks 1 and 4: 5-74 on 9 targets, 9-125 on 12. Missed Weeks 2 and 3. Week 5 is Monday night.
199 yards in two games, including 125 at Philadelphia in his return from hip and groin injuries.
Why each side can win
The Cardinals
Brissett has thrown for 1,110 yards and 9 touchdowns, McBride has at least 7 catches in every game, and Wilson keeps drawing targets. Arizona already won once in Los Angeles this season, 26-14 at the Chargers in Week 1.
The Rams
Los Angeles is at home, allows 255.8 yards a game and swept Arizona by 28 and 17 points last season. The Cardinals have allowed 37 points a game during a four-game losing streak and just traded their former No. 4 pick.
Records, venue, spread and total from the ESPN scoreboard, read 2026-10-12.1
Implied points is half the total moved half the spread, which is arithmetic on the two numbers above, not a projection.
What the market says
The posted line has Los Angeles Rams favoured by 12.5, with a total of 52.5. A spread is the market's estimate of the margin, not a result; the Kalshi contract below prices the win outright.
The two venue prices sit at the top of this page and are read live when it loads. A
contract settles at $1.00 if that team wins and $0 if it loses, so a price in cents is
that market’s implied chance of the win. Prices are the venues’, not our picks,
and the two rarely agree to the cent.
A spread and a contract price are two different questions. The spread is the market’s
estimate of the margin; the contract prices the win outright, and it is the one you can sell
before the game ends. Books differ on the spread itself: our read found two games where a
second book had a different number the same afternoon.1
Cardinals vs Rams player props on Kalshi
Every player contract Kalshi has listed for this game, live: passing, rushing and
receiving yards, receptions, carries and touchdowns. Each chip is a threshold and the
price to buy YES on it.
Reading the Kalshi board.
Trading it: the case each way
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about the game itself.
The question on Arizona Cardinals
Arizona Cardinals are 1-4 and they are on the road, and the line makes them the underdog by 12.5. Decide what chance you
would give them, in cents, before you read the board. If your number is above the ask,
that is the trade; if it is not, there is no trade here.
The question on Los Angeles Rams
Los Angeles Rams are 2-2 and favoured by 12.5. A favourite contract costs most of a dollar, so the
money at risk is large against the money to be made. Work out what you lose if it goes
wrong before you decide what you make if it goes right.
Whatever you decide, write the entry, the sell target and the hold rule
before kickoff, and remember the fee is largest near 50¢.
How the fee works
Questions people ask about this game
Who is favored in Cardinals vs Rams on October 18, 2026?
The Los Angeles Rams are 12.5-point favorites over the Arizona Cardinals at DraftKings, with the Rams at -675, the Cardinals at +490 and a total of 52.5, as read October 12, 2026. Lines move through the week.
What time is Cardinals vs Rams and what channel is it on?
The Cardinals play the Rams on Sunday, October 18, 2026, at 4:05 PM ET (1:05 PM PT) at SoFi Stadium in Inglewood, California. The game is on Fox.
Is Marvin Harrison Jr. still on the Cardinals?
No. Arizona traded Harrison to the Houston Texans during its 45-21 loss to Detroit on October 11. He had 5 catches for 85 yards and a touchdown in four games for the Cardinals this season.
Will Myles Garrett play for the Rams against the Cardinals?
Garrett is on injured reserve after knee surgery. On October 10, Sean McVay said it was more likely the Rams would not open his 21-day practice window the following week. ESPN lists an October 25 return.
What happened the last time the Cardinals played the Rams?
The Rams won 37-20 in Los Angeles on January 4, 2026, after beating Arizona 45-17 in Arizona on December 7, 2025. The Cardinals finished last season 3-14.
What is Agent Brad’s parlay for Cardinals vs Rams?How many points is each team priced for in Arizona Cardinals at Los Angeles Rams?
Half the total moved half the spread puts Arizona Cardinals at about 20 points and Los Angeles Rams at about 32.5. That is arithmetic on the two posted numbers, not a score projection, and it is the figure most fantasy decisions on this game turn on.
How often does each leg of a pick'em entry need to hit to break even?
A pick'em entry is a parlay, so every leg has to land: two legs you price at 60 per cent are 36 per cent together, and three are 22 per cent. If your board pays N times the entry on an L-leg play, the entry needs to win one divided by N of the time, so each leg needs the L-th root of that. A two-leg play paying 3x needs each leg at about 57.7 per cent, and a four-leg play paying 10x needs each at about 56.2 per cent. Multipliers differ by state, board and promotion, so use your own terms.
Sources
Every stored figure on this page came from one of these, read 2026-10-12. Lines move
and injury news lands after that; the prices in the strip and on the board are read live when
the page loads, not written into it.
ESPN NFL scoreboard: schedule, records, venue, broadcast, the posted spread and the total. site.api.espn.com
ESPN NFL game summaries for the completed Week 1 to Week 5 games: the five-game player totals, summed from the box scores. espn.com
Kalshi public markets API, the Arizona Cardinals at Los Angeles Rams game market: the contract this page links to. Prices are read live in your browser, never stored here. external-api.kalshi.com
The headline on this page: The Cardinals traded Marvin Harrison Jr. Read 2026-10-12. www.cbssports.com
PM Countdown is not affiliated with or endorsed by Kalshi, Polymarket, ESPN or
the NFL. Prices shown are the venues’, not our picks.
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